Samuel L. Jackson
Major Marquis Warren

Kurt Russell
John 'The Hangman' Ruth

Jennifer Jason Leigh
Daisy Domergue

Walton Goggins
Sheriff Chris Mannix

Demián Bichir
Bob

Tim Roth
Oswaldo Mobray

Michael Madsen
Joe Gage

Bruce Dern
General Sandy Smithers

James Parks
O. B. Jackson

Dana Gourrier
Minnie

Zoë Bell
'Six-Horse' Judy

Lee Horsley
Ed

Gene Jones
Sweet Dave

Keith Jefferson
Charly

Craig Stark
Chester Charles Smithers

Belinda Owino
Gemma

Channing Tatum
Jody

Quentin Tarantino
Narrator (voice) (uncredited)